---
title: "Hotel Isa vs Twenty One Hotel: which hotel is better?"
description: "Hotel Isa or Twenty One Hotel in Rome? Compare guest ratings, location, amenities, rooms and prices side by side."
url: https://stayversus.com/en/compare/hotel-isa-rome-vs-twenty-one-hotel-rome/
language: en
source: StayVersus (https://stayversus.com)
retrieved: 2026-11-05
---

# Hotel Isa vs Twenty One Hotel

Both are in Rome, 250 m apart. Here is where each one is stronger.

Hotel · ★★★★ · Prati
## [Hotel Isa](https://stayversus.com/en/hotel/hotel-isa-rome/)

- **Guest rating:** 9.2 ·  Excellent

- **Location score:** 8.0

- **Score by category:** 1 of 3

[Check rates](https://stayversus.com/go/1589031/agoda/?lang=en)

Hotel · ★★★★ · Prati
## [Twenty One Hotel](https://stayversus.com/en/hotel/twenty-one-hotel-rome/)

- **Guest rating:** 8.2 ·  Very good

- **Location score:** 8.1

- **Score by category:** 0 of 3

[Check rates](https://stayversus.com/go/2251612/agoda/?lang=en)

The short answer

## Too close to call

Neither hotel has a clear edge on the facts we have. Your priorities decide. 250 m apart.

### Choose Hotel Isa if you want

-   the more consistently praised stay (9.2 / 8.2)
-   breakfast included

### Why is Hotel Isa better than Twenty One Hotel?

1.  Higher guest rating (9.2 vs 8.2) (+1.0)
2.  Includes free breakfast

### Why is Twenty One Hotel better than Hotel Isa?

1.  More guest reviews (293 vs 6), so the rating is more reliable (×49)

## All compared facts

Every category is scored from 0 to 10 with the same formula for every hotel.

 

|  | Hotel Isa | Twenty One Hotel |
| --- | --- | --- |
| Score by category |
| Guest rating | 9.2  (+1.0) | 8.2 |
| Location | 8.0 | 8.1 |
| Facilities | – | 8.3 |
| Spa & wellness | – | 1.5 |
| Public transport | 5.7 | 6.0 |
| Ratings & reviews |
| StayVersus score | 8.5  (+0.2) | 8.2 |
| Guest rating | 9.2  (+1.0) | 8.2 |
| Number of reviews | 6 | 293  (+287) |
| Rank in Rome | top 37%  (+29%) | bottom 34% |
| Location |
| Location score | 8.0 | 8.1 |
| Distance to Prati centre | 370 m | 350 m |
| To public transport | 950 m | 890 m |
| To the airport | 16 km | 16 km |
| Restaurants within 500 m | 150 | 150 |
| To the nearest food shop | 110 m | 160 m |
| Shops within 500 m | 13 | 16  (+3) |
| Sights within 1 km | 40 | 40 |
| Rooms & building |
| Star rating | ★★★★ | ★★★★ |
| Rooms | – | 96 |
| Floors | – | 5 |
| Newest building or renovation | – | 2010 |
| Listed amenities | 11 | 22  (+11) |
| Policies |
| Check-in from | 15:00 | 15:00 |
| Check-out until | 11:00 | 11:00 |
| Amenities |
| Free Wi-Fi | ✓ | ✓ |
| Parking | ✓ | ✓ |
| 24-hour front desk | ✓ | ✓ |
| Free breakfast | ✓ | – |
| Bar | ✓ | ✓ |
| Wheelchair accessible | ✓ | – |
| Minibar | ✓ | ✓ |
| In-room safe | ✓ | ✓ |
| Airport transfer | – | ✓ |
| Shuttle | – | ✓ |
| Car hire | – | ✓ |
| Concierge | – | ✓ |
| Laundry | – | ✓ |
| Luggage storage | – | ✓ |
| Restaurant | – | ✓ |
| 24-hour room service | – | ✓ |
| Gym | – | ✓ |
| Terrace | – | ✓ |
| Air conditioning | – | ✓ |
| Balcony | – | ✓ |
| Coffee or tea maker | – | ✓ |
| Distance to the main sights |
| Colosseum | 2.6 km | 2.8 km |
| St. Peter's Basilica | 1.4 km | 1.5 km |
| Roman Forum | 2.1 km | 2.3 km |
| Trevi Fountain | 1.3 km | 1.5 km |
| Archbasilica of St. John Lateran | 3.8 km | 4.0 km |
| Castel Sant'Angelo | 480 m  (−220 m) | 700 m |
| Which hotel suits you |
| Spa & relaxation | – | ✓ |

## Live prices around both hotels

Real nightly rates from booking partners for the dates you picked above. Tap a price for the offer.

## Location

250 m apart

Hotel Isa: city centre: 1.2 km, nearest station Ottaviano – San Pietro – Musei Vaticani: 950 m, Ciampino–G. B. Pastine International Airport (CIA): 16 km, 150+ places to eat within 500 m, 40+ sights within 1 km.

Twenty One Hotel: city centre: 1.4 km, nearest station Ottaviano – San Pietro – Musei Vaticani: 890 m, Ciampino–G. B. Pastine International Airport (CIA): 16 km, 150+ places to eat within 500 m, 40+ sights within 1 km.

[Top-rated of 127 hotels in Prati](https://stayversus.com/en/italy/rome/area/prati/)

## Weather in Rome

[Rome weather: 15-day forecast](https://atlasofseasons.com/en/italy/lazio/rome/weather)

## Hotel Isa or Twenty One Hotel: common questions

### Which is better, Hotel Isa or Twenty One Hotel?

Hotel Isa leads in 1 of 3 categories, including guest rating.

### Which is cheaper, Hotel Isa or Twenty One Hotel?

Prices change by date. Pick your dates above to see both nightly prices side by side.

### How far apart are Hotel Isa and Twenty One Hotel?

The two hotels are 250 m apart in a straight line.

## Compare now

Updated 6 Oct 2026. Data: Agoda, Overture Maps, OpenStreetMap, OurAirports and hotels' own websites. We may earn a commission from partner links; it never changes the comparison. [How we score](https://stayversus.com/en/about/)

---
Source: https://stayversus.com/en/compare/hotel-isa-rome-vs-twenty-one-hotel-rome/. Facts are compiled by StayVersus from partner data (Agoda), Overture Maps, OpenStreetMap, OurAirports, public Google Maps listings and hotels' own websites. Scores use one formula for every hotel. Methodology: https://stayversus.com/en/about/