Isa Design Hotel vs Twenty One Hotel
Both are in Rome, 230 m apart. Here is where each one is stronger.
Hotel★★★★Prati
Isa Design Hotel
- Guest rating
- 8.7 Very good
- Location score
- 8.1
- Score by category
- 1 of 5
Hotel★★★★Prati
Twenty One Hotel
- Guest rating
- 8.2 Very good
- Location score
- 8.1
- Score by category
- 2 of 5
The short answer
Pick Twenty One Hotel
It leads in 2 of 5 categories. 230 m apart.
Choose Isa Design Hotel if you want
- the more consistently praised stay (8.7 / 8.2)
- a smaller, quieter hotel (Rooms: 50 / 96)
- a newer or recently renovated building (2016 / 2010)
Choose Twenty One Hotel if you want
- a big hotel with more facilities (Rooms: 96 / 50)
Why is Isa Design Hotel better than Twenty One Hotel?
- 1Higher guest rating (8.7 vs 8.2)+0.5
- 2Newer or more recently renovated (2016 vs 2010)+6y
Why is Twenty One Hotel better than Isa Design Hotel?
- 1More guest reviews (293 vs 133), so the rating is more reliable×2.2
- 25 more listed amenities (22 vs 17)+5
- 3Has a gym
- 4Has 24-hour room service
- 5Has an on-site restaurant
All compared facts
Every category is scored from 0 to 10 with the same formula for every hotel.
| Isa Design Hotel vs Twenty One Hotel: which hotel is better? | Isa Design Hotel | Twenty One Hotel |
|---|---|---|
| Score by category | ||
| Guest rating | 8.7 +0.5 | 8.2 |
| Location | 8.1 | 8.1 |
| Facilities | 5.0 | 8.3 +3.3 |
| Spa & wellness | 0.0 | 1.5 +1.5 |
| Public transport | 5.9 | 6.0 |
| Ratings & reviews | ||
| StayVersus score | 8.6 +0.4 | 8.2 |
| Guest rating | 8.7 +0.5 | 8.2 |
| Number of reviews | 133 | 293 +160 |
| Rank in Rome | top 21% +45% | bottom 34% |
| Location | ||
| Location score | 8.1 | 8.1 |
| Distance to Prati centre | 330 m | 350 m |
| To public transport | 920 m | 890 m |
| To the airport | 16 km | 16 km |
| Restaurants within 500 m | 150 | 150 |
| To the nearest food shop | 110 m | 160 m |
| Shops within 500 m | 14 | 16 |
| Sights within 1 km | 40 | 40 |
| Rooms & building | ||
| Star rating | ★★★★ | ★★★★ |
| Rooms | 50 | 96 |
| Floors | 4 | 5 |
| Newest building or renovation | 2016 +6y | 2010 |
| Listed amenities | 17 | 22 +5 |
| Policies | ||
| Check-in from | 15:00 | 15:00 |
| Check-out until | 11:00 | 11:00 |
| Amenities | ||
| Free Wi-Fi | ✓ | ✓ |
| Airport transfer | ✓ | ✓ |
| Shuttle | ✓ | ✓ |
| Car hire | ✓ | ✓ |
| Concierge | ✓ | ✓ |
| Laundry | ✓ | ✓ |
| Luggage storage | ✓ | ✓ |
| Breakfast | ✓ | ✓ |
| Bar | ✓ | ✓ |
| Terrace | ✓ | ✓ |
| Air conditioning | ✓ | ✓ |
| Balcony | ✓ | ✓ |
| Minibar | ✓ | ✓ |
| In-room safe | ✓ | ✓ |
| Blackout curtains | ✓ | – |
| Parking | – | ✓ |
| 24-hour front desk | – | ✓ |
| Restaurant | – | ✓ |
| 24-hour room service | – | ✓ |
| Gym | – | ✓ |
| Coffee or tea maker | – | ✓ |
| Distance to the main sights | ||
| Colosseum | 2.7 km | 2.8 km |
| St. Peter's Basilica | 1.4 km | 1.5 km |
| Roman Forum | 2.1 km | 2.3 km |
| Trevi Fountain | 1.4 km | 1.5 km |
| Archbasilica of St. John Lateran | 3.9 km | 4.0 km |
| Castel Sant'Angelo | 480 m −220 m | 700 m |
| Which hotel suits you | ||
| Spa & relaxation | – | ✓ |
Price for your dates
Prices come from booking partners and can change. The final price is shown before you book.
Live prices around both hotels
Real nightly rates from booking partners for the dates you picked above. Tap a price for the offer.
Location
230 m apart
Isa Design Hotel: city centre: 1.2 km, nearest station Ottaviano – San Pietro – Musei Vaticani: 920 m, Ciampino–G. B. Pastine International Airport (CIA): 16 km, 150+ places to eat within 500 m, 40+ sights within 1 km.
Twenty One Hotel: city centre: 1.4 km, nearest station Ottaviano – San Pietro – Musei Vaticani: 890 m, Ciampino–G. B. Pastine International Airport (CIA): 16 km, 150+ places to eat within 500 m, 40+ sights within 1 km.
Top-rated of 127 hotels in Prati
Weather in Rome
Isa Design Hotel or Twenty One Hotel: common questions
Which is better, Isa Design Hotel or Twenty One Hotel?
Twenty One Hotel leads in 2 of 5 categories, including facilities, spa & wellness. Isa Design Hotel is stronger in guest rating.
Which is cheaper, Isa Design Hotel or Twenty One Hotel?
Prices change by date. Pick your dates above to see both nightly prices side by side.
How far apart are Isa Design Hotel and Twenty One Hotel?
The two hotels are 230 m apart in a straight line.
Compare now
Updated 6 Oct 2026. Data: Agoda, Overture Maps, OpenStreetMap, OurAirports and hotels' own websites. We may earn a commission from partner links; it never changes the comparison. How we score